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Discovery Platform

AlloMAp

AlloMAp (Allosteric Modulator Aptamer) Platform

Innovative therapeutic aptamer development platform that modulates function through allosteric binding to cell membrane receptors

Developmental platform of the aptamer-based allosteric therapeutics

Allosteric therapeutics

Benefits
- Higher specificity
- Diverse signal transduction
- Better safety (Saturability)

Hurdles
- Unpredictable allosteric site
- Proper binding surface is needed

Aptamer Science’s competitive technology

- ViroSELEX technique for membrane protein-targeting aptamer discovery
- Ligand screening technique (LIGAND-SCAN)
- Aptamer archive for over 200 membrane proteins

Main pipeline

AST-101 | AST-102

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